Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery.
نویسندگان
چکیده
Novel mesoporous silica nanoparticles (MSNs) responsive to multiple biological stimuli (pH and enzymes) were prepared through conjugation with a structure modified soy protein isolate. The particles show an extremely high pro-drug (sulfasalazine) loading with programmable drug release in simulated gastrointestinal fluid.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 42 شماره
صفحات -
تاریخ انتشار 2014